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However, some of these recommendations might not be appropriate for certain patients, including diabetic patients with gastroparesis (slow stomach emptying) who may not be able to increase fiber-rich foods, and patients with significant obesity in whom physical activity is a barrier
For example, GLP-1 modulates glutamate-induced Ca 2+ influx in neuronal cell cultures
There are no robust human safety data yet
Candidates typically have a BMI of 27 or higher with a weight-related condition, or a BMI of 30+
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