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Protocol 4: nasal spray approach Goal: Needle-free administration with acceptable bioavailability trade-off Duration: 20 days active, then 4-6 months off Schedule: Days 1-20: 10-15 mg epitalon intranasally, divided into 2-3 daily doses Days 21-180: Off cycle Repeat 1-2 times per year Formulation: Reconstitute in saline with 3 percent DMSO for improved nasal absorption
It plays a central role in: Neutralizing reactive oxygen species (free radicals) Supporting liver detoxification pathways Maintaining immune and mitochondrial health Protecting proteins and DNA from oxidative damage Low glutathione levels or an impaired glutathione system are associated with increased oxidative stress, which contributes to fatigue, inflammation, and slower recovery
Li C, Schluesener H
