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The economic burden is considerable: annual direct healthcare costs attributable to MASLD in the United States and Europe are estimated in the tens of billions of dollars, driven by hospitalizations, liver-related procedures, and management of comorbid conditions [6]

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More recently, GLP-1 RA drugs have been approved for weight loss, cardiovascular disease, and chronic kidney disease

The association for bipolar disorder was significant in Hou Ls study (OR = 0.90, 95% CI [0.88, 0.93]) but lacked statistical significance in Stahl Es analysis