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Nonetheless, current evidence supports melatonins use for improving sleep and circadian alignment in aging, which itself can confer systemic benefits (better sleep can improve memory consolidation, metabolic regulation, and mood, indirectly supporting healthier aging) (Zhang et al., 2025)
No, berberine does not feature in NICE guideline NG28 for type 2 diabetes management and has no MHRA-approved therapeutic indication in the UK
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Consulting a healthcare professional before starting supplementation ensures that you are taking the right amount for your individual needs
11 , X1986449 (2019)
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