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Liu DX, Zhao CS, Wei XN, Ma YP, Wu JK

153 Simultaneously, IL-1 stimulates macrophages and other immune cells to activate the NLRP3 inflammasome, leading to the cleavage of pro-IL-1 into its mature, biologically active form

4 Department of Natural and Life Sciences, Long Island University, Brooklyn, NY, 11201, USA Correspondence: Dong H Kwon, Department of Natural and Life Sciences, Long Island University, 1 University Plaza, Brooklyn, NY, 11201, USA, Tel +1 718 780 4098, Fax +1 718 488 1465, Email [email protected] Abstract: Antibiotic resistance has spread globally among bacterial pathogens, becoming a significant challenge to public health