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Results indicated slowed bone loss and improved bone structure [56]

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Second, added GIP agonism improves insulin sensitivity more strongly, and cortisol-driven weight problems are usually insulin-resistance problems at their core

Patients should be advised to: Drink 1.5 to 2 litres of water daily (unless fluid restriction is medically indicated for conditions such as heart failure or chronic kidney disease) Increase fluid intake during episodes of nausea, vomiting, or diarrhoea Monitor urine colourpale straw colour indicates adequate hydration Avoid excessive caffeine and alcohol, which can irritate the bladder and act as diuretics Dietary and lifestyle measures can also help manage urinary symptoms