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TRIUMPH-1 trajectory (80 weeks + extension): Week 80: 28.3% average weight loss (2,339 patients) 104-week extension (BMI 35 subgroup): 30.3% average weight loss Weight loss does not plateau at 80 weeks it continues in longer treatment The TRIUMPH-1 104-week extension is the most important long-term efficacy signal we have
The primary adverse effects associated with its use are gastrointestinal issues
Initial Treatment Phase Within Days of Starting Many people notice nausea within the first few days as their digestive system and appetite signals begin to adjust
Appetite Regulation and CNS Research The amylin receptors distribution in appetite-regulating and reward-related brain regions makes cagrilintide a tool for CNS research on food intake regulation
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