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Cagrilintide is a 39amino-acid peptide with structural modifications (including an N-terminal fatty diacid chain) designed to improve stability and reduce fibril formation compared with native amylin
Enhanced mucus secretion/production and/or abnormal mucus properties are associated with several airway diseases, as highlighted in this review
4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas
However, these alterations did not rescue enzymatic activity (Fig
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