Steroids are controlled substances that are regulated by government agencies, but peptides tend to be widely available
A significant decrease was also noted in the plasma concentrations of non-enzymatic antioxidants: hydrophilic ascorbic acid and hydrophobic -tocopherol
The efficacy is attributed to the reduction in the synthesis of purine and pyrimidines, ATP, GTP, CTP, and TTP, along with the targeting of the TCA cycle metabolites, i.e., fumarate, malate, aspartate, and citrate, as well as NADH, essential for proper mitochondrial function
The clinical significance of this difference remains an area of ongoing discussion among practitioners