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The compound binds the growth-hormone-releasing-hormone receptor on somatotrophs, mimicking endogenous GHRH and triggering an adenylyl-cyclase / cAMP / protein-kinase-A signalling cascade
Clin Exp Reprod Med
Researchers believe that GLP1 receptor activation may reduce airway inflammation by: Modulating immune responses, including dampening the activity of inflammatory cells like eosinophils and T-helper cells Lowering oxidative stress, which damages airway tissues Potentially affecting smooth muscle responsiveness in the airways These effects suggest that GLP1 therapies could play a beneficial role in asthma symptom controlespecially for patients with overlapping metabolic issues
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