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Metabolomics of gWAT revealed that NDI1 expression led to an increase in abundance of several nucleotides (NAD + , ATP, GTP) and succinic acid, a reduction in pyruvic acid and -ketoglutarate, and an increase in the NAD + -to-NADH and ATP-to-ADP ratios (Fig
While their approach successfully employed LC-MS for metabolic profiling, it relied on in vivo 15 N uniform metabolic labeling to achieve accurate quantification
Cancer Ther., 2017, 16, 871
It inhibits the pigment responsible for dark spots and uneven skin tone, leading to a more even complexion and reduced hyperpigmentation
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