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Anyone with metabolic, cardiac, GI, hepatic, or renal disease or who is pregnant, breastfeeding, or planning pregnancy should not consider it without licensed clinical care
Nevertheless, studies utilizing more specific biomarkers of vitamin B 12 status, including measures of holo-transcobalamin and methylmalonic acid, have shown more consistent results and a trend towards associations between poor vitamin B 12 status and faster cognitive decline and increased risk of Alzheimers disease (82-86)
The most prominent immunological manifestation is the production of antibodies directed against self-antigens
Patient researchers often achieve better long-term outcomes than those who push too hard too fast
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