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Primary murine PDAC cells were derived from Kras tm1Tyj : Kras LSL-G12D/+ + Trp53 tm1Brn : Trp53 fl/fl + Ptf1a tm1(Cre)Hnak : Ptf1a Cre-ex1/+ (KPC) compound mutant mouse tumors and were prepared as fragments for outgrowth culture

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