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No, depression and mood changes are not currently listed as recognised side effects in the MHRA-approved Summary of Product Characteristics for Mounjaro (tirzepatide)
Key conjugation reactions include: glutathione S-transferase (GST) conjugation, glucuronidation (UGT), sulfation (SULT), methylation (COMT, TPMT), acetylation (NAT), and amino acid conjugation (glycine, taurine)
This is called triple chronotherapy and has been shown to improve sleep parameters in people with circadian rhythm disorders and those with depression and bipolar disorder
While you might find compounded tirzepatide pills online, the FDA hasnt tested them to ensure they actually work or are safe to use
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