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The influence mediated by HGF secretion and HGF-induced MET activation in all these studies provides an evidence that, beyond stem-cell ability to differentiate into neurons, the secretion of paracrine growth factors such as HGF provides an important regenerative capacity and a promising therapeutic tool

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Rat studies showing Achilles tendon healing, rabbit studies showing bone repair not human clinical trials

1a), and all treatments lead to decreased cell viability, as measured by annexin V-PI assay (Fig