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This is particularly relevant in cytoprotective investigations where mucosal barrier reinforcement is the primary research objective
It plays a role in many functions, including antioxidant defenses, nutrient metabolism, the regulation of cellular events (including gene expression and cell proliferation), and immune response
If a reduction in the amount of glucose-6-phosphate dehydrogenase or alteration of structure occurs due to G6PD gene mutations, the enzyme loses its protective role, leading to the accumulation of reactive oxygen species and thus damaging red blood cells
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