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The 7,8-DHF erythrocyte distribution is unknown, and erythrocyte distribution likely has little contribution to the brain concentration correction ( 2.5 Exploratory analysis of 7,8-DHF metabolites The semi-quantitative plasma and brain O-methylated 7,8-DHF metabolite concentrations were summarized using descriptive statistics (mean and standard deviation) at each time point
Due to neurons having a limited capacity for GSH synthesis, they must rely on astrocytes to supply precursors such as cysteine (Prez-Sala D and Pajares, 2023)
NAC is a form of the amino acid cysteine, which is essential for glutathione synthesis
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