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Insulin, GLP-1 receptor agonists, teriparatide and approved endocrine and reproductive peptides have genuinely changed clinical practice
Nevertheless, the expression of these NKG2D ligands open the way to use CAR-T cell therapy based on the recognition of these molecules overexpressed on the cell surface of senescent cells
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They can also help offer pain relief, reduce inflammation, and promote healing in areas damaged by trauma or surgery
Evidence is currently preclinical
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