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More than 900 drugs have been implicated in causing liver injury [1] (see LiverTox, external link, below) and it is the most common reason for a drug to be withdrawn from the market

The authors proposed that melanocortin signaling may intersect with pigment associated mechanisms involved in oxidative stress buffering, drawing parallels between eumelanin synthesis in melanocytes and neuromelanin accumulation within specific neuronal populations

It stabilizes delicate mitochondrial membranes, significantly reduces the generation of destructive reactive oxygen species (ROS), and protects the cell from ferroptosis, a severe form of iron-dependent cell death