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An analysis published in JAMA Internal Medicine in 2022 found that patients using GLP-1 receptor agonists had a higher incidence of gallbladder-related events compared to those using other diabetes medications
Related animal studies have further affirmed that Liraglutide can effectively suppress liver cancer progression in mouse models of diabetes and nonalcoholic steatohepatitis (NASH) [44]
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While GLP-1 receptor agonist therapy leads to greater relative fat loss than lean mass loss, preserving muscle tissue requires adequate protein intake and resistance exercise during weight reduction
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