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characterized a mouse model of ALS with a mutant mtSOD1 gene with a Glycine to Alanine substitution (SOD1G93A) to clarify the etiology of the disease (Soares et al., 2023)
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This gives the neural tissue a higher susceptibility to peroxidation ( Parkinsons Disease (PD) Pathogenesis: Role of Oxidative Stress, Mitochondrial Dysfunction, and Neuroinflammation Parkinsons disease is a chronic, progressive neurodegenerative disorder involving the dopaminergic neurons in the substantia nigra pars compacta of the brain ( Dopamine Metabolism The neurotransmitter dopamine itself can be a source of oxidative stress
Furthermore, some medications may interfere with glutathione levels, so its crucial to inform our healthcare practitioners about any medications you are currently taking
