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If the pomegranate extract increased intestinal absorption of L-carnitine, a greater proportion of the ingested dose would be taken up before reaching the colon, theoretically reducing the substrate available to TMA-producing gut microbiota and thereby lowering TMAO production through a mechanism independent of direct microbial inhibition
Systemic action means the compound affects the entire body
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When to seek medical care Severe persistent vomiting, signs of pancreatitis (severe upper-abdominal pain, often radiating to the back), severe allergic reactions, or any reaction that is getting worse rather than better are reasons to stop and seek qualified medical care
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