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Dihexa was designed specifically to survive first-pass metabolism better than parent angiotensin IV analogs, but most vendor oral capsule claims are not supported by peer-reviewed pharmacokinetic data in humans

Other frequently encountered causes include: Thyroid disorders both hypothyroidism and hyperthyroidism can cause diffuse hair thinning Iron deficiency anaemia one of the most common nutritional causes of hair loss, particularly in women Alopecia areata an autoimmune condition causing patchy hair loss Telogen effluvium triggered by physical or emotional stress, illness, surgery, significant weight loss, or the postpartum period Polycystic ovary syndrome (PCOS) associated with hormonal imbalances that affect hair growth Traction alopecia caused by prolonged tension on the hair from certain hairstyles Tinea capitis a fungal scalp infection, particularly relevant in children Scarring alopecias a group of conditions causing permanent follicle destruction

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