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So this is very much evolving in real time
Adding semaglutide does not increase seizure risk directly, but rapid weight loss combined with medication changes requires careful monitoring
MahmoudianDehkordi S, Ahmed AT, Bhattacharyya S, Han X, Baillie RA, Arnold M, et al
It has been suggested that a delay in gastric emptying may also contribute to the changes in pharmacokinetics (33% increase in AUC 048 h ) observed for levothyroxine when coadministered with oral semaglutide in a study of 45 healthy volunteers
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