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They have revolutionized the way clinicians treat obesity as a chronic condition while simultaneously highlighting the inequity and opaqueness around pharmacy drug pricing practices, said Nelsie Nelson, Sequoias director of pharmacy
Sikiric P, Seiwerth S, et al
The evidence consistently identifies several factors that increase risk further: Higher doses (the weight-loss doses of semaglutide and tirzepatide carry higher risk than the lower diabetic doses) Longer duration of treatment Faster rate of weight loss Pre-existing gallstones even asymptomatic ones found on a previous scan Female sex, age over 40, and family history of gallstones (the standard baseline risk factors, amplified by GLP-1 therapy) If several of these apply to you, the risk-benefit balance of your treatment plan is worth a structured discussion
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