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According to FDA labeling, patients frequently experience: Nausea (reported in 44-73% of patients on higher doses) Vomiting (15-27% of patients on higher doses) Diarrhea (30-47% of patients on higher doses) Constipation (19-28% of patients on higher doses) Abdominal pain or discomfort Decreased appetite (intended therapeutic effect) These gastrointestinal symptoms typically emerge during dose escalation, are dose-dependent, and often improve over time as the body adjusts

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