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Peroxisome proliferator activated receptors play a significant role in energy homeostasis, oxidative stress, fatty acid metabolism by mitochondria, and inflammation
Sustained exposure was defined as redeeming at least one prescription for the assigned drug class in every 6-month interval, with no redeemed prescriptions for the comparator class in those intervals
Most research supports doses between 200-400 mcg daily for general metabolic support, while specialized applications may utilize higher doses up to 1000 mcg
Mild to moderate nausea, temporary acid reflux, or temporary feelings of heavy stomach fullness
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