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Why timing and dose sometimes dont fix interactions Some interactions are pharmacokinetic and can be mitigated by spacing doses

Materials and Methods Fluorescent instrumentation Perkin-Elmer fluorescent spectrometer model 1000 set at excitation wavelength 475nm and its scale expansion gain control knob was adjusted so that a 10M solution of the bimane conjugate gave a full scale reading of 100 fluorescence units

Given sex imbalance across groups, sex-stratified analyses were conducted

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