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What leaders should know: Oral cheaper for insured members (pricing is often comparable) Easier access may drive higher utilization and faster spend growth Adherence and outcomes arent guaranteed with daily dosing Benefit design and pharmacy strategy will determine whether this helps or hurts budgets The opportunity isnt the pill
it demands a nuanced understanding of potency, indication, and titration to avoid adverse effects and ensure therapeutic success
Pregnancy and breastfeeding represent absolute contraindications based on precautionary principles
Pros: simple to place does not require repeated clinic/hospital visits, Cons: Psychological implications of having a semi-permanent tube drain inserted Requires training for management Higher risk for infection Pleurodesis In MPE patients with expandable lungs, talc slurry pleurodesis may improve quality of life, chest pain, breathlessness and pleurodesis rates
