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Lowering GSH levels also triggers ferroptosis through deactivation of GPX4, leading to accumulation of lipid peroxides [87] In some cases, GSH depletion alone can induce therapeutic effects without relying on Fenton chemistry, which typically involves HO reacting with Fe 2 to form hydroxyl radicals (OH) that damage critical biomolecules such as DNA, proteins, and lipids
It has also shown success in Phase II trials for ophthalmic repair and dry eye
Meanwhile, the formula takes dark spot correction a step further by pairing niacinamide with Melasyla proprietary ingredient designed to interfere with excess melanin production that contributes to hyperpigmentation
Author: By Karla K
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