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PubMed laboratory research record [PMID: 35485358] PubMed record related to this compound for laboratory literature review
In DUAL-1 the A1c reduction from baseline with IDegLira was somewhat higher (estimated difference of 0.21%) in patients in use of pioglitazone and metformin compared to those with metformin alone (A1c for IDegLira 1.8% in the metformin subgroup and 2.1% in the metformin plus pioglitazone subgroup
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As this subgroup of ASD patients have several parallels with the rodent PPA model of ASD, 13 this rodent model may be a useful tool to further examine the temporal relation of behavioral bouts in relation to carnitine-acyl-carnitine fluctuations, and their possible response to therapeutic compounds thought to be useful in the treatment of ASD and mitochondrial dysfunction such as carnitine supplementation
