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A few key points: Yes, semaglutide can cause diarrhea, and its among the most common side effects

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Retatrutide looks more mechanistically aggressive: CagriSema looks more like an incremental combination of two better-understood pathways

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Dihexa's synaptogenic effects require activation of the c-Met receptor, as demonstrated by experiments using c-Met-specific short hairpin RNA (shRNA) which completely abolished Dihexa's capacity to induce spine formation

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