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doi: 10.1023/a:1018955126402 105 BeckDESweeneyWBMcCarterMDIpamorelin 201 Study Group

The consideration of cysteine during these simulations were important, as cytosolic cysteine is the rate limiting amino acid precursor for synthesis of GSH, via the -glutamylcysteine synthetase (GCS) enzyme, and this is a function of its reduced concentration compared to the other precursors, glycine and glutamate

Those protons re-enter the matrix by traveling through a pore in ATP synthase, and the released energy is used to make ATP, increasing the ATP/ADP ratio