Once in the mitochondrial matrix, the acyl group of the acylcarnitine is cleaved, and can enter beta oxidation
The most common side effects of tirzepatide are gastrointestinal, including nausea (12-24%), diarrhea (12-17%), vomiting (6-10%), constipation (6-11%), and decreased appetite
This exposure can lead to a range of neurodevelopmental and physical symptoms, including cognitive impairments, developmental delays, autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), and congenital malformations
280 : 17771782 Rosler M, Anand R, Cicin-Sain A, Gauthier S, Agid Y, Dal-Bianco P et al