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Firstly, long-chain fatty acids are converted to long-chain acyl-CoA catalyzed by acyl-CoA synthetases in the endoplasmic reticulum and outer mitochondrial membrane
The simultaneous activation of these G protein receptor signaling pathways on the islet cells may lead to additional antagonistic or synergistic interactions, but this is unknown
World J Gastroenterol 23:5146 Dooley S, ten Dijke P (2012) TGF- in progression of liver disease
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