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Diabetologia 58, 21242132
(Research has identified mast cells as one of the immune cell types involved in the inflammatory cascades that influence arterial plaque development and lipid-related cardiovascular risk, as I note in my MCAS info page.) In neurological disease , research in animal models of stroke and vascular dementia has shown that GLP-1RAs reduce both microglial activation and neuroinflammation, leading to better protection of the brain from injury and cognitive deterioration
Its especially promising for people with metabolic syndrome, diabetes, or those already on BP meds
Gradual Uptitration: Patients are closely monitored as the dose is gradually increased in increments of 0.1mg every few weeks, based on individual response and tolerability
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