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All animal protocols done by TechMedILL service were reviewed and approved by the agriculture ministry regulating animal research in France (Ethics regional committee for animal experimentation Strasbourg, APAFIS 1341#2015080309399690)
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By combining Keap1 inhibitors with H2S-donor moieties via molecular hybridization, DDO-1901 showed enhanced efficacy in alleviating colitis by mitigating oxidative stress and inflammation, outperforming parent drugs alone (263)
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