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Very high-intensity training or significant caloric deficit from excessive exercise can suppress the hypothalamic-pituitary-ovarian (HPO) axis, leading to disrupted ovulation, a condition known as hypothalamic amenorrhoea. Your goal is consistent, moderate activity rather than intense training regimens
Seventy percent ethanol extract was provided at doses of 300, 600 and 1200 mg/kg to genetically obese in Zucker rats resulting in a reduction of circulating GLP-1 by acting on GLP-1 receptors [32]
Lyons D, Louly Nathan A, Pender E, Murray G, Smith C, Kirby B, et al
The bigger picture is that GLP-1 therapy is a tool, not a personality transplant
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