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Side effects of semaglutide for weight loss Common side effects of semaglutide include: Nausea Vomiting Diarrhea Constipation Abdominal pain Gastrointestinal problems Serious side effects of the medication include: Diabetic retinopathy (changes in vision) Acute pancreatitis Gallbladder problems Hypoglycemia (low blood sugar levels) Mood changes and suicidal ideation Increased risk of aspiration during sedation and anesthesia Acute kidney injury Allergic or hypersensitivity reaction Semaglutide is not recommended for patients with a history of thyroid tumors (medullary thyroid cancer) and endocrine tumors such as MEN 2 (multiple endocrine neoplasia type 2 syndrome)
Clinical trials have demonstrated superior outcomes, with participants losing about 15% of their body weight
Other off-label uses for semaglutide include nonalcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS)
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