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These differences matter clinically: larger average weight loss translates into bigger improvements in blood pressure, glycemic measures, sleep apnea metrics, mobility, and quality of life for many patients
Retatrutide (LY3437943) is a synthetic 39-amino-acid peptide studied in preclinical research as a triple agonist of the glucose-dependent insulinotropic polypeptide receptor (GIPR), the glucagon-like peptide-1 receptor (GLP-1R), and the glucagon receptor (GCGR)
Morton RW, Murphy KT, McKellar SR, et al
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