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no hepatic safety signal has been observed across the orforglipron clinical program, distinguishing it from the discontinued Pfizer oral GLP-1 candidates lotiglipron and danuglipron, both of which were terminated due to liver toxicity concerns
(7) D A York, S Boghossian, and M Park-York (2011) Melanocortin activity in the amygdala influences alcohol intake Pharmacology, Biochemistry & Behavior, 2011 Mar, Volume 98 (Issue 1), Pages 112-9
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