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Research on humans and rodents indicates that intrahepatic hypothyroidism (resulting from elevated deiodinase 3 activity or reduced THR- expression) is a key factor in MASH
Known as vitamin A, retinol is an essential lipid-soluble antioxidant in animals
The study authors suspect weight loss drives this effect, though GLP-1 agonists may also influence testosterone through their impact on inflammation and hormone signaling in the brain
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