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Methods We used a mouse model of global Taz knockdown ( Taz -KD) and combined in vivo and in vitro approaches to assess pancreatic islet metabolism, morphology and hormone secretion

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Background Chemical Properties Quality Control User Guide Background FOXO4-DRI is a cell-permeable peptide antagonist.FOXO4-DRI is an anti-aging peptide that induces apoptosis in senescent cells

Naturally occurring amylin is co-secreted with insulin by pancreatic beta cells to assist in glycemic regulation and satiety, but its brief biological half-life limits its utility in long-term laboratory models