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In mammalian cells, glutathione primarily exists in the reduced state at moderate concentrations and in an extremely high proportion, effectively scavenging reactive intermediates produced spontaneously by cells or from external toxic factors, thereby protecting the cells

But they come at a steep cost

Because these compounds are naturally occurring peptides with restricted patentability, opportunities for intellectual property protection and industry-sponsored development are limitedposing substantial barriers to the resource-intensive clinical investigations required to confirm therapeutic efficacy and long-term safety

Mediterranean diet improves cognition: the PREDIMED-NAVARRA randomised trial