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La GLP-1 endgena tiene una vida media de aproximadamente 2-3 minutos porque es rpidamente degradada por la enzima dipeptidil peptidasa-4 (DPP-4)
In preclinical efficacy studies in diet-induced obese (DIO) mice and obese monkeys, treatment with AMG133 reduces body weight and improves metabolic parameters to a larger extent than a GLP-1 receptor agonist alone (50)
facility under strict compounding standards
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