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The pathophysiology of severe asthma with persistent airflow limitation shares similar features with that of chronic obstructive pulmonary disease (COPD), including airway remodeling and emphysema-like changes, which complicate diagnosis and treatment [42]
They work at different biological layers: GHK-Cu at the dermis and ECM level, retinol at the epidermis and receptor level
Peptide Sequence (IUPAC Condensed): H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH
Model robustness was assessed using Receiver Operating Characteristic - Area Under Curve (ROC-AUC) analysis in MetaboAnalyst software
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