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Another SURMOUNT-3 analysis 208 demonstrated that tirzepatide improved health-related quality of life scores in obese/overweight adults, with greater benefits observed in those achieving higher weight loss thresholds and in those without baseline functional limitations
But sustained loss of more than 2 pounds weekly over a month or more indicates an excessive deficit that is almost certainly including muscle tissue
Hubbard CS, Karpowicz JM, Furman AJ, da Silva JT, Seminowicz DA, Traub RJ
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