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MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis
Upon release, Nrf2 translocates to the nucleus where it can bind to the antioxidant response element (ARE) located in the promoter region of genes coding for antioxidant enzymes and scavengers
It inhibits tyrosinase, the enzyme that pigment-producing cells (melanocytes) use to make melanin
J Contemp Dent Pract
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