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CQ4-15 (p 109), CQ4-20 (p 124), Nankodo, Tokyo, 2020 (Book in Japanese, ISBN: 978-524-22545-3)

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Interestingly, the observation of weight loss in individuals with type 2 diabetes treated with GLP-1 RAs prompted investigations into their potential use for obesity management and a decade ago, the first GLP-1RA was approved for this indication 1,810

A study on an older GLP-1 agonist, liraglutide, included data on the weight loss achieved at lower doses, demonstrating effectiveness even during the ramp-up phase