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its real-world effectiveness depends heavily on the patients ability to stick to the morning routine
However, it has notable downsides: Cognitive side effects (brain fog, memory issues, difficulty concentrating) Can cause depression and mood instability Often leads to significant tingling sensations in the extremities Not as effective as newer weight-loss drugs Metformin Metformin is primarily used for type 2 diabetes but is sometimes prescribed off-label for weight loss due to its effects on insulin sensitivity and appetite
Ann N Y Acad Sci 2004;1033:30-41
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